Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484922 | 1.00 | RIPK1 (0.55) | RIPK1LMNAKDM4EL3MBTL1CYP2C19 | |
| Sulfuric Acid SCHEMBL11756260 | 0.91 | RIPK1 (0.47) | RIPK1LMNAKDM4EL3MBTL1CYP2C19 | |
| SCHEMBL2745411 | 0.90 | RIPK1 (0.53) | RIPK1LMNAKDM4EL3MBTL1CYP2C19 | |
| SCHEMBL9226022 | 0.86 | RIPK1 (0.50) | RIPK1LMNAKDM4EL3MBTL1CYP2C19 | |
| SCHEMBL10187504 | 0.84 | SRD5A2 (0.44) | RIPK1 | |
| SCHEMBL9405193 | 0.81 | PTGS1 (0.47) | RIPK1KDM4EL3MBTL1AOC3 | |
| SCHEMBL8510683 | 0.80 | HRH1 (0.50) | LMNACYP2C19 | |
| SCHEMBL244975 | 0.80 | CYP2C19 (0.42) | RIPK1LMNAKDM4EL3MBTL1CYP2C19 | |
| SCHEMBL2690630 | 0.80 | CYP2C19 (0.40) | RIPK1CYP2C19 | |
| SCHEMBL2691428 | 0.80 | AOC3 (0.44) | RIPK1LMNAL3MBTL1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3093780-A | — | — | None | — | — | JP | disclosed |
| CN-117603027-A | Olefin difunctional method and delta-trifluoromethyl ketone product prepared by same | 重庆理工大学 | 2024-02-27 | — | — | CN | disclosed |
| EP-3953324-A1 | PHOTOREDOX CATALYICALLY SELECTIVE ACTIVATION OF SULPHUR HEXAFLUORIDE FOR ALPHA-ALKOXY PENTAFLOUORSULFONATION OF UNSATURATED HYDROCARBON COMPOUNDS AND DERIVATISATION TO FORM UNSATURATED PENTAFLOUORSULFANES | Karlsruher Institut für Technologie (DE) | 2022-02-16 | — | — | EP | disclosed |
| WO-2020207620-A1 | PHOTOREDOX CATALYICALLY SELECTIVE ACTIVATION OF SULPHUR HEXAFLUORIDE FOR ALPHA-ALKOXY PENTAFLOUORSULFONATION OF UNSATURATED HYDROCARBON COMPOUNDS AND DERIVATISATION TO FORM UNSATURATED PENTAFLOUORSULFANES | Karlsruher Institut für Technologie (DE) | 2020-10-15 | — | — | WO | disclosed |
| US-20130123253-A1 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2013-05-16 | — | — | US | disclosed |
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-1797082-B1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-8168635-B2 | 2-(aminomethyl)-5-phenyltetrahydrofuran; 4-(3,4-Dimethoxyphenyl)-2-[5-(2-{5-[2-(5-fluoro-2-methoxyphenyl)-ethyl]-tetrahydrofuran-2-yl}-ethylamino)-pentyl]-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one; dual inhibitor of serotonin reuptake and phosphodiesterase 4 (PDE4) enzyme activity | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-05-01 | — | — | US | disclosed |
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2010-10-14 | — | — | US | disclosed |
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN | 2002-12-05 | — | — | US | disclosed |
| EP-1157020-B1 | SUBSTITUTED 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCIN-10-OLS, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001094355-A1 | CROSS-COUPLING REACTION OF ORGANOSILICON NUCLEOPHILES | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2001-12-13 | — | — | WO | disclosed |
| EP-1157020-A1 | SUBSTITUTED 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCIN-10-OLS, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2001-11-28 | — | — | EP | disclosed |
| US-6245777-B1 | SODIUM CHANNEL MODULATORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-12 | — | — | US | disclosed |
| WO-2000050421-A1 | SUBSTITUTED 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCIN-10-OLS, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-08-31 | — | — | WO | disclosed |
| EP-0570401-B1 | LIPOXYGENASE-INHIBITING HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES | PFIZER (US) | 1994-11-09 | — | — | EP | disclosed |
| EP-0570401-A1 | LIPOXYGENASE-INHIBITING HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES. | PFIZER (US) | 1993-11-24 | — | — | EP | disclosed |
| WO-1992013848-A1 | LIPOXYGENASE-INHIBITING HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES | PFIZER INC. (US) | 1992-08-20 | — | — | WO | disclosed |
| JP-H0393780-A | PRODUCTION OF 2-(1-HYDROXYALKYL) TETRAHYDROFURANS | MITSUI PETROCHEM IND LTD | 1991-04-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | TST, HPD, PCNA | RIPK1 3343/4885LMNA 4232/4885KDM4E 2413/4885 |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | GTF2F1, F3, GTF2F2 | RIPK1 1141/4885LMNA 4860/4885KDM4E 3919/4885 |
| US-20130123253-A1 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | GAP43, SLC18A2, CHRNA6 | RIPK1 2121/4885LMNA 2315/4885KDM4E 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.