Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398255 | 0.89 | AOC3 (0.50) | KDM4EAOC3CYP2C19TSHRALDH1A1 | |
| SCHEMBL3273377 | 0.85 | AOC3 (0.46) | KDM4EAOC3CYP2C19TSHRALDH1A1 | |
| SCHEMBL9641990 | 0.85 | KDM4E (0.54) | KDM4EAOC3TSHRALDH1A1RET | |
| SCHEMBL19723310 | 0.83 | AOC3 (0.49) | KDM4EAOC3CYP2C19TSHRALDH1A1 | |
| SCHEMBL9748515 | 0.79 | RIPK1 (0.47) | KDM4EAOC3CYP2C19TSHRALDH1A1 | |
| SCHEMBL8557986 | 0.78 | ALDH1A1 (0.52) | KDM4EAOC3TSHRALDH1A1RET | |
| SCHEMBL13699528 | 0.78 | ALDH1A1 (0.52) | KDM4EAOC3TSHRALDH1A1RET | |
| SCHEMBL7437735 | 0.76 | OPRK1 (0.44) | AOC3KMT2AMEN1TAAR1OPRM1 | |
| Hydrochloric Acid SCHEMBL3273754 | 0.76 | ALDH1A1 (0.54) | KDM4EAOC3TSHRALDH1A1RET | |
| SCHEMBL10672887 | 0.76 | AOC3 (0.62) | KDM4EAOC3CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080940-A2 | Derivatives of 2-phenyl-morpholine and medical compositions | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1983-06-08 | — | — | EP | disclosed |