Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13369291 | 0.82 | ADRA2A (0.39) | MAP3K14ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL8250545 | 0.78 | POLB (0.41) | MAP3K14KDM4EMAPT | |
| SCHEMBL13444800 | 0.76 | ITGB2 (0.41) | MAP3K14CYP3A4MAPK1CYP19A1 | |
| SCHEMBL14183091 | 0.76 | MAP3K14 (0.67) | TMEM97HTR2BSIGMAR1MAOAMAOB | |
| SCHEMBL1111009 | 0.76 | MAP3K14 (0.67) | TMEM97HTR2BSIGMAR1MAOAMAOB | |
| SCHEMBL1570063 | 0.76 | MAOA (0.41) | TMEM97HTR2BSIGMAR1MAOAMAOB | |
| SCHEMBL18998244 | 0.75 | MAOA (0.45) | TMEM97HTR2BSIGMAR1MAOAMAOB | |
| SCHEMBL13893989 | 0.74 | MAOA (0.45) | TMEM97HTR2BSIGMAR1MAOAMAOB | |
| SCHEMBL27339090 | 0.74 | MAOA (0.45) | TMEM97HTR2BSIGMAR1MAOAMAOB | |
| SCHEMBL20831832 | 0.74 | ALDH1A1 (0.52) | MAOBMEN1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230475-B1 | NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |