Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | CCKAR | P32238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748884 | 1.00 | SLC6A4 (0.33) | SLC6A4SLC6A3HMGCRKDM4EL3MBTL1 | |
| SCHEMBL9749709 | 0.80 | PTGS2 (0.32) | SLC6A4SLC6A3HMGCRMEN1ALDH1A1 | |
| SCHEMBL9749704 | 0.80 | PTGS2 (0.32) | SLC6A4SLC6A3HMGCRMEN1ALDH1A1 | |
| SCHEMBL10408051 | 0.73 | HMGCR (0.35) | HMGCRKDM4EALDH1A1LMNAABCC3 | |
| SCHEMBL10408048 | 0.73 | HMGCR (0.35) | HMGCRKDM4EALDH1A1LMNAABCC3 | |
| SCHEMBL9845366 | 0.72 | HMGCR (0.35) | HMGCRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9845407 | 0.70 | HMGCR (0.34) | HMGCRKDM4EALDH1A1LMNAABCC3 | |
| SCHEMBL9845413 | 0.70 | HMGCR (0.34) | HMGCRKDM4EALDH1A1LMNAABCC3 | |
| SCHEMBL9845410 | 0.70 | HMGCR (0.34) | HMGCRKDM4EALDH1A1LMNAABCC3 | |
| SCHEMBL9803101 | 0.69 | ITGB1 (0.34) | HMGCRABCC3ABCB11PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114964-A | Aryl-substituted benzocycloalkyl-derived anti-atherosclerotic agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-05-19 | — | — | US | disclosed |