SCHEMBL9748973

SCHEMBL9748973

COC1(C)CCc2ccc(O)cc2O1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CA2 P00918 1/20 0.40
CA5A P35218 1/20 0.40
AKT1 P31749 1/20 0.39
ESR2 Q92731 5/20 0.39
ESR1 P03372 4/20 0.39
MAPT P10636 1/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
BCHE P06276 1/20 0.36
MALT1 Q9UDY8 1/20 0.36
OPRM1 P35372 2/20 0.35
OPRD1 P41143 2/20 0.35
OPRK1 P41145 2/20 0.35
CHRNA7 P36544 1/20 0.35
TTR P02766 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9749407 0.88 AKT1 (0.51) ALDH1A1KDM4EAKT1ESR2ESR1
SCHEMBL27889129 0.85 ESR2 (0.42) ALDH1A1KDM4ECA2CA5AAKT1
SCHEMBL31254037 0.80 ALDH1A1 (0.49) ALDH1A1KDM4ECA2CA5AAKT1
SCHEMBL4974003 0.80 ALDH1A1 (0.49) ALDH1A1KDM4ECA2CA5AAKT1
SCHEMBL10527939 0.77 SIGMAR1 (0.41) ALDH1A1OPRM1
SCHEMBL6798457 0.77 SOD1 (0.44) ALDH1A1KDM4ECA2CA5ALMNA
SCHEMBL6798455 0.77 SOD1 (0.44) ALDH1A1KDM4ECA2CA5ALMNA
SCHEMBL6799093 0.77 SOD1 (0.44) ALDH1A1KDM4ECA2CA5ALMNA
Formaldehyde SCHEMBL27953583 0.76 ALDH1A1 (0.49) ALDH1A1KDM4ECA2CA5AAKT1
SCHEMBL9354890 0.75 ALDH1A1 (0.41) ALDH1A1KDM4EESR2ESR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63203677-A None JP disclosed
EP-0230475-B1 NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-03-18 EP disclosed
US-4838924-A NONPHYTOTOXIC MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-06-13 US disclosed
JP-S63203677-A 2,3-DIHYDROBENZOPYRANS AND PRODUCTION THEREOF MITSUI PETROCHEM IND LTD 1988-08-23 JP disclosed