Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549947 | 0.77 | LMNA (0.47) | LMNATDP1CNR2ROCK2ROCK1 | |
| SCHEMBL1061793 | 0.77 | AKR1C3 (0.46) | LMNATDP1CNR2POLBMEN1 | |
| SCHEMBL1767596 | 0.77 | AKR1C3 (0.46) | LMNATDP1CNR2POLBMEN1 | |
| SCHEMBL5512525 | 0.75 | KMT2A (0.51) | LMNATDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11121078 | 0.74 | ELANE (0.44) | LMNAOGFRL1 | |
| SCHEMBL27274109 | 0.72 | KDM4E (0.47) | POLBSMN1; SMN2 | |
| SCHEMBL10864406 | 0.71 | KMT2A (0.55) | KMT2APPARG | |
| SCHEMBL2588918 | 0.71 | KMT2A (0.55) | KMT2APPARG | |
| SCHEMBL28258003 | 0.71 | ROCK2 (0.61) | LMNATDP1ROCK2ROCK1MEN1 | |
| SCHEMBL10444427 | 0.70 | HPGD (0.41) | LMNATDP1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196222-B1 | HYPOGLYCEMIC AGENT | AJINOMOTO CO., INC. (JP) | 1992-01-29 | — | — | EP | disclosed |