Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748869 | 0.83 | KMT2A (0.45) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9749016 | 0.81 | KMT2A (0.45) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9748822 | 0.81 | KDM4E (0.44) | KDM4EKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL10060155 | 0.69 | KDM4E (0.58) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL4122649 | 0.68 | KMT2A (0.58) | KDM4EKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL3263722 | 0.67 | HPGDS (0.57) | KDM4EMAPTALDH1A1MAPK1HSD17B10 | |
| SCHEMBL10546359 | 0.67 | NPC1 (0.47) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL22886768 | 0.67 | CDC25B (0.44) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3062533 | 0.67 | KMT2A (0.57) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL25177257 | 0.65 | S1PR1 (0.45) | KDM4EKMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224842-B1 | PYRAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND HERBICIDE CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |