Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749016 | 0.86 | KMT2A (0.45) | KMT2ARAB9ANPC1KDM4EPOLB | |
| SCHEMBL9748822 | 0.86 | KDM4E (0.44) | KMT2ARAB9ANPC1KDM4EPOLB | |
| SCHEMBL9749032 | 0.83 | KDM4E (0.40) | KMT2ARAB9ANPC1KDM4ETP53 | |
| SCHEMBL10921548 | 0.80 | TDP2 (0.42) | KMT2ARAB9ANPC1KDM4EHSD17B10 | |
| SCHEMBL10918426 | 0.79 | GRM6 (0.42) | KMT2ARAB9ANPC1KDM4ETP53 | |
| SCHEMBL10928298 | 0.79 | KDM4E (0.49) | KMT2ARAB9ANPC1KDM4ETP53 | |
| SCHEMBL1969117 | 0.78 | HPGDS (0.59) | KMT2ARAB9ANPC1KDM4ETP53 | |
| SCHEMBL5065916 | 0.76 | JAK2 (0.52) | KMT2ARAB9ANPC1KDM4ELMNA | |
| SCHEMBL9748942 | 0.76 | KDM4E (0.43) | KMT2ARAB9AKDM4ETP53HSD17B10 | |
| SCHEMBL25211948 | 0.74 | ALDH1A1 (0.55) | KMT2AKDM4EHSD17B10ADORA3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224842-B1 | PYRAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND HERBICIDE CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |