Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269746 | 0.85 | HPGDS (0.61) | HPGDSADORA3SMN1; SMN2MAPTKDM4E | |
| SCHEMBL1969117 | 0.82 | HPGDS (0.59) | HPGDSADORA3SMN1; SMN2MAPTKDM4E | |
| SCHEMBL17279852 | 0.80 | HPGDS (0.60) | HPGDSADORA3SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10924593 | 0.80 | HPGDS (0.56) | HPGDSADORA3SMN1; SMN2MAPTKDM4E | |
| SCHEMBL3847496 | 0.77 | HPGDS (0.60) | HPGDSADORA3SMN1; SMN2MAPTKDM4E | |
| SCHEMBL27321802 | 0.76 | RAB9A (0.63) | HPGDSADORA3SMN1; SMN2MAPTKDM4E | |
| SCHEMBL14747477 | 0.76 | HPGDS (0.52) | HPGDSADORA3SMN1; SMN2MAPTKDM4E | |
| SCHEMBL13495378 | 0.76 | SMN1; SMN2 (0.52) | HPGDSADORA3SMN1; SMN2MAPTKDM4E | |
| SCHEMBL2375452 | 0.75 | TTK (0.52) | HPGDSSMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL10172532 | 0.75 | HPGDS (0.60) | HPGDSADORA3SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |