Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749074 | 0.81 | MAPT (0.41) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9739607 | 0.74 | S1PR2 (0.35) | KMT2AKDM4E | |
| SCHEMBL7235960 | 0.67 | MEN1 (0.49) | MEN1KMT2AAGPAT2ALDH1A1L3MBTL1 | |
| SCHEMBL11022815 | 0.66 | S1PR2 (0.38) | KMT2A | |
| SCHEMBL9741185 | 0.66 | KMT2A (0.47) | MEN1KMT2AKDM4E | |
| SCHEMBL7185382 | 0.66 | SNCA (0.48) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9749087 | 0.66 | MEN1 (0.35) | MEN1KMT2AAGPAT2CYP3A4 | |
| SCHEMBL9234031 | 0.65 | KMT2A (0.46) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9741145 | 0.65 | CYP1A2 (0.53) | KMT2AALDH1A1KDM4E | |
| SCHEMBL3794354 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126454-A | PROCESS FOR THE PREPARATION OF SULPHONYLISOUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |