SCHEMBL9748885

SCHEMBL9748885

CCOC(=O)c1c(-c2ccc3ccccc3n2)n[nH]c1S(=O)(=O)Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
PRNP P04156 1/20 0.39
MAPT P10636 5/20 0.38
POLB P06746 1/20 0.38
LMNA P02545 2/20 0.38
HPGDS O60760 1/20 0.38
ADORA3 P0DMS8 1/20 0.37
TP53 P04637 1/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
HPGD P15428 2/20 0.37
NPC1 O15118 1/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9749658 0.85 POLB (0.37) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL9749076 0.84 ADORA3 (0.43) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL9748942 0.82 KDM4E (0.43) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL9747984 0.82 MEN1 (0.42) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL10514632 0.81 LMNA (0.44) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL10924357 0.75 CDC7 (0.44) SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
SCHEMBL9749174 0.74 TSHR (0.45) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL7808722 0.72 PDE4D (0.63) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
Ethyl Acetate SCHEMBL29082170 0.68 KMT2A (0.54) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL28609425 0.68 RAB9A (0.55) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0224842-B1 PYRAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND HERBICIDE CONTAINING IT NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-02-05 EP disclosed