Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | TOP2A | P11388 | 4/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750330 | 0.84 | KDM4E (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9748366 | 0.84 | LMNA (0.66) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9749223 | 0.84 | LMNA (0.66) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9376194 | 0.83 | TOP2A (0.56) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9837318 | 0.82 | TOP2A (0.55) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9838719 | 0.82 | KDM4E (0.59) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9750360 | 0.82 | EPHA2 (0.54) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9750369 | 0.82 | EPHA2 (0.54) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9146445 | 0.81 | PIM1 (0.49) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9146453 | 0.81 | PIM1 (0.49) | LMNAMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091383-A | SUBSTITUTED BRIDGED DIAZABICYCLOALKYL QUINOLONE CARBOXYLIC ACIDS | PFIZER INC. (US) | 1992-02-25 | — | — | US | disclosed |