Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 7/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | RPA1 | P27694 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974906 | 0.89 | MARS1 (0.50) | MARS1SMPD1FAAHRPA1CNR1 | |
| SCHEMBL9418677 | 0.81 | MARS1 (0.72) | MARS1SMPD1FAAHRXRANR1H2 | |
| SCHEMBL2982610 | 0.77 | RPA1 (0.73) | MARS1SMPD1RPA1CNR1SMN1; SMN2 | |
| SCHEMBL31130516 | 0.76 | SLC16A3 (0.64) | MARS1SMPD1FAAHRPA1CNR1 | |
| SCHEMBL29419072 | 0.74 | RXRA (0.62) | MARS1SMPD1RXRANR1H2NR1H3 | |
| SCHEMBL341019 | 0.74 | RXRA (0.62) | MARS1SMPD1RXRANR1H2NR1H3 | |
| SCHEMBL9418696 | 0.72 | MARS1 (0.59) | MARS1SMPD1RXRANR1H2NR1H3 | |
| SCHEMBL29419099 | 0.70 | MARS1 (0.68) | MARS1SMPD1FAAHRPA1LMNA | |
| SCHEMBL342100 | 0.70 | MARS1 (0.68) | MARS1SMPD1FAAHRPA1LMNA | |
| SCHEMBL31130515 | 0.70 | SLC16A3 (0.63) | FAAHRXRANR1H2NR1H3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021771-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021771-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC11, HDAC3 | MARS1 1832/4885SMPD1 1060/4885FAAH 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.