Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749614 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9748472 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9749529 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9749534 | 0.75 | APEX1 (0.54) | ALDH1A1HPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL10360761 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9749375 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9749369 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9749606 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9749602 | 0.72 | PPARA (0.50) | ALDH1A1HPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL9749240 | 0.71 | L3MBTL1 (0.41) | ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |