Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21524721 | 0.84 | CA2 (0.41) | BRD4CREBBPESR1ESR2CYP3A4 | |
| SCHEMBL8584200 | 0.74 | CYP3A4 (0.48) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL16448787 | 0.74 | CYP3A4 (0.48) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL9749477 | 0.73 | ESR1 (0.41) | BRD4CREBBPESR1ESR2CYP3A4 | |
| SCHEMBL30703071 | 0.73 | POLB (0.44) | BRD4CREBBPMEN1KMT2AMAOA | |
| SCHEMBL28910133 | 0.72 | CYP19A1 (0.48) | ESR1ESR2CYP3A4MAOACA2 | |
| SCHEMBL5547664 | 0.70 | BRD4 (0.55) | BRD4CREBBPESR1ESR2MAPT | |
| SCHEMBL5821844 | 0.69 | BRD4 (0.44) | BRD4CREBBPESR1ESR2MEN1 | |
| SCHEMBL18643710 | 0.69 | CREBBP (0.44) | BRD4CREBBPMAPTTHRBKMT2A | |
| SCHEMBL30438928 | 0.69 | CHRNB4 (0.52) | BRD4CREBBPESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230475-B1 | NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |