Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 3/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.50 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026294 | 0.82 | DDX3X (0.63) | CRHBPCRHR2MEN1KMT2AALDH1A1 | |
| SCHEMBL3619602 | 0.82 | ALDH1A1 (0.51) | CRHBPCRHR2TSHRMEN1KMT2A | |
| SCHEMBL10619003 | 0.82 | FFAR4 (0.53) | CRHBPCRHR2MEN1KMT2AALDH1A1 | |
| SCHEMBL3791578 | 0.79 | TSHR (0.74) | CRHBPCRHR2TSHRMEN1KMT2A | |
| SCHEMBL1970882 | 0.79 | CRHBP (0.72) | CRHBPCRHR2TSHRMEN1KMT2A | |
| SCHEMBL7569069 | 0.78 | TSHR (0.58) | CRHBPCRHR2TSHRMEN1KMT2A | |
| SCHEMBL11872858 | 0.77 | DDX3X (0.71) | CRHBPCRHR2TSHRMEN1KMT2A | |
| SCHEMBL28711028 | 0.77 | ALDH1A1 (0.70) | CRHBPCRHR2MEN1KMT2AALDH1A1 | |
| SCHEMBL30561863 | 0.76 | ALDH1A1 (0.66) | CRHBPCRHR2KMT2AALDH1A1MAPT | |
| SCHEMBL2003165 | 0.76 | ALDH1A1 (0.66) | CRHBPCRHR2KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132461-A | Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitro-benzene | WELLA AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | disclosed |
| US-4900869-A | Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitrobenzene | Wella, Aktiengesellschaft (DE) | 1990-02-13 | — | — | US | disclosed |