Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 13/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064772 | 1.00 | HCAR2 (0.48) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL29222103 | 0.98 | HCAR2 (0.46) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL27869371 | 0.93 | HCAR2 (0.43) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL6150290 | 0.91 | HCAR2 (0.45) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL15260447 | 0.91 | HCAR2 (0.45) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL29148759 | 0.91 | HCAR2 (0.45) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL27558800 | 0.89 | HCAR2 (0.41) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL5681276 | 0.89 | HCAR2 (0.44) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL28896894 | 0.87 | ALDH1A1 (0.56) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL6403988 | 0.87 | ALDH1A1 (0.56) | HCAR2TSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106190936-B | Bacterium and construction method and application thereof | 上海交通大学 | 2020-07-10 | — | — | CN | claimed |
| CN-106190901-B | Bacterium and obtaining method and application thereof | 上海交通大学 | 2020-06-26 | — | — | CN | claimed |
| CN-106190936-B | Bacterium and construction method and application thereof | 上海交通大学 | 2020-07-10 | — | — | CN | disclosed |
| CN-106190901-B | Bacterium and obtaining method and application thereof | 上海交通大学 | 2020-06-26 | — | — | CN | disclosed |
| WO-2016164810-A1 | PLANTS WITH ENHANCED YIELD AND METHODS OF CONSTRUCTION | METABOLIX, INC. (US) | 2016-10-13 | — | — | WO | disclosed |
| US-20140134687-A1 | MODIFIED MICROORGANISMS AND METHODS OF USING SAME FOR PRODUCING BUTADIENE AND SUCCINATE | BRASKEM S/A AP 09 (BR) | 2014-05-15 | — | — | US | disclosed |
| US-5112834-A | Antisecretory and antiulcer | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-05-12 | — | — | US | disclosed |
| WO-1985002116-A1 | MEDIUM FOR STORING BLOOD PLATELETS | THOMAS JEFFERSON UNIVERSITY (US) | 1985-05-23 | — | — | WO | disclosed |
| US-4145557-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4062895-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | ELI LILLY AND COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-4001322-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3972934-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |