SCHEMBL6403988

SCHEMBL6403988

CCCC(=O)OC(=O)/C=C\C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
HCAR2 Q8TDS4 8/20 0.53
TSHR P16473 2/20 0.38
ATM Q13315 1/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
FFAR3 O14843 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ACHE P22303 1/20 0.34
BACE1 P56817 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28896894 1.00 ALDH1A1 (0.56) ALDH1A1HCAR2TSHRATMTP53
SCHEMBL6403998 1.00 ALDH1A1 (0.56) ALDH1A1HCAR2TSHRATMTP53
SCHEMBL7763367 0.91 ALDH1A1 (0.67) ALDH1A1HCAR2TSHRATMFFAR3
SCHEMBL28098612 0.91 ALDH1A1 (0.67) ALDH1A1HCAR2TSHRATMFFAR3
SCHEMBL5064772 0.87 HCAR2 (0.48) ALDH1A1HCAR2TSHRATMTP53
SCHEMBL9749521 0.87 HCAR2 (0.48) ALDH1A1HCAR2TSHRATMTP53
SCHEMBL28382057 0.87 HCAR2 (0.47) ALDH1A1HCAR2ATMACHEBACE1
SCHEMBL29074633 0.86 HCAR2 (0.58) ALDH1A1HCAR2TSHRATM
SCHEMBL668234 0.85 HCAR2 (0.59) ALDH1A1HCAR2TSHRTDP1
SCHEMBL18209635 0.85 HCAR2 (0.59) ALDH1A1HCAR2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115403704-A Method for producing latex composition for dip forming 锦湖石油化学株式会社 2022-11-29 CN disclosed
US-6939601-B2 obtained by applying an unpigmented intermediate coat to a substrate to be coated,crosslinking the intermediate coat and forming an intermediate coat layer,applying an unpigmented top-coat , crosslinking; flexibility; automobiles BOLLIG & KEMPER GMBH & CO. KG (DE) 2005-09-06 US disclosed
US-20040121160-A1 obtainable by applying unpigmented intermediate coat to substrate to be coated, crosslinking intermediate coat, applying unpigmented top-coat to intermediate coat layer, crosslinking top coat; automobiles; impact resistance, gloss PPG COATINGS DEUTSCHLAND GMBH (DE) 2004-06-24 US disclosed