SCHEMBL9749580

SCHEMBL9749580

FC(F)(F)c1nc(Cl)cc(S)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
XPO1 O14980 1/20 0.33
GLP1R P43220 1/20 0.33
ATF1 P18846 1/20 0.32
NFKB1 P19838 1/20 0.32
ENPP3 O14638 1/20 0.32
ENPP1 P22413 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30872394 0.80 GLP1R (0.41) XPO1GLP1RATF1NFKB1ENPP3
SCHEMBL9749212 0.72
SCHEMBL30911120 0.68 ENPP1 (0.41) XPO1GLP1RATF1NFKB1ENPP3
SCHEMBL10858879 0.68 ENPP1 (0.34) GLP1RATF1NFKB1ENPP3ENPP1
SCHEMBL9749216 0.67
SCHEMBL31288083 0.65 HTT (0.38) XPO1GLP1RATF1NFKB1
SCHEMBL29300827 0.65 ENPP3 (0.36) XPO1GLP1RATF1NFKB1ENPP3
SCHEMBL24027389 0.65 TRPV4 (0.39)
SCHEMBL9750279 0.65 NT5E (0.37)
SCHEMBL20796970 0.65 ENPP1 (0.46) XPO1ENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5087699-A Chemical intermediate for pyridinethiolate nickel complex; light stabilizers, infrared absorbers and chelate compounds RICOH COMPANY, LTD. (JP) 1992-02-11 US disclosed