Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | PDCD4 | Q53EL6 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749592 | 1.00 | S1PR1 (0.39) | S1PR1S1PR3DAGLAS1PR2PDCD4 | |
| SCHEMBL9749608 | 0.92 | DAGLA (0.36) | DAGLAPDCD4NOD1KMT2A | |
| SCHEMBL14339054 | 0.81 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9671381 | 0.81 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9745643 | 0.80 | PDCD4 (0.38) | DAGLAPDCD4CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL10430991 | 0.79 | S1PR1 (0.43) | S1PR1S1PR3S1PR2PDCD4NR4A2 | |
| SCHEMBL8985047 | 0.78 | PRKCA (0.40) | PDCD4LMNA | |
| SCHEMBL9672430 | 0.78 | NAAA (0.40) | DAGLAPDCD4 | |
| SCHEMBL9745619 | 0.78 | PRKCA (0.37) | DAGLAPDCD4MAPK1LMNA | |
| SCHEMBL9327478 | 0.76 | PTPN1 (0.42) | DAGLAMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0369811-A2 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |