Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749631 | 1.00 | LDHA (0.45) | LDHAKDM4EMEN1MAPTKMT2A | |
| SCHEMBL1831426 | 0.84 | KDM4E (0.38) | LDHAKDM4EMEN1MAPTKMT2A | |
| SCHEMBL7971777 | 0.83 | KDM4E (0.55) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL3817099 | 0.83 | KDM4E (0.55) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL3817101 | 0.83 | KDM4E (0.55) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL8830501 | 0.77 | CRHBP (0.53) | LDHAKDM4EKMT2A | |
| SCHEMBL8830506 | 0.77 | CRHBP (0.53) | LDHAKDM4EKMT2A | |
| SCHEMBL7419712 | 0.75 | NR4A1 (0.39) | LDHAKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL11829415 | 0.74 | NFKB1 (0.46) | KDM4EMAPT | |
| SCHEMBL909267 | 0.73 | KDM4E (0.42) | KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201071-B1 | 2-SUBSTITUTED-1-NAPHTHOLS AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-03-04 | — | — | EP | claimed |