Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748757 | 0.86 | GAA (0.49) | ALDH1A1HSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL18256086 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL9749252 | 0.77 | GAA (0.51) | ALDH1A1HSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL8551184 | 0.75 | L3MBTL1 (0.42) | ALDH1A1HSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL13471437 | 0.73 | ALDH1A1 (0.71) | ALDH1A1HSD17B10HPGDESR1GAA | |
| SCHEMBL13277864 | 0.72 | GAA (0.56) | ALDH1A1HSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL9748472 | 0.69 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL10691191 | 0.68 | ALDH1A1 (0.40) | ALDH1A1HSD17B10GAAL3MBTL1KDM4E | |
| SCHEMBL2213342 | 0.68 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL20749226 | 0.66 | CYP4F2 (0.41) | ALDH1A1HSD17B10HPGDGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |