Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056221 | 0.84 | TRPM8 (0.46) | L3MBTL1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL18256086 | 0.84 | ALDH1A1 (0.43) | L3MBTL1CYP4F2CYP4A11MAPTTSHR | |
| SCHEMBL9749629 | 0.75 | ALDH1A1 (0.53) | L3MBTL1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL27834209 | 0.72 | L3MBTL1 (0.55) | L3MBTL1CYP4F2CYP4A11MAPTTSHR | |
| SCHEMBL10685599 | 0.72 | HSD17B10 (0.40) | L3MBTL1MAPTTSHRALDH1A1HSD17B10 | |
| SCHEMBL8061952 | 0.72 | CYP1A2 (0.38) | ALDH1A1GAACYP1A2 | |
| SCHEMBL20749226 | 0.72 | CYP4F2 (0.41) | L3MBTL1CYP4F2CYP4A11MAPTTSHR | |
| Acetic Acid SCHEMBL8056225 | 0.71 | ALDH1A1 (0.33) | L3MBTL1MAPTTSHRALDH1A1HPGD | |
| SCHEMBL1566852 | 0.71 | CYP4F2 (0.40) | L3MBTL1CYP4F2CYP4A11MAPTTSHR | |
| SCHEMBL1808600 | 0.70 | ALDH1A1 (0.58) | MAPTTSHRALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |