Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749968 | 0.88 | MAPT (0.47) | MAPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9750076 | 0.86 | ALDH1A1 (0.41) | MAPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9749975 | 0.83 | ALDH1A1 (0.47) | MAPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9750417 | 0.80 | MAPT (0.42) | MAPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9838423 | 0.79 | MAPT (0.41) | MAPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9750060 | 0.79 | RAB9A (0.43) | MAPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9750085 | 0.79 | NPC1 (0.50) | MAPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9750097 | 0.78 | ALDH1A1 (0.40) | MAPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9749572 | 0.77 | ALDH1A1 (0.45) | MAPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9750078 | 0.76 | MAPT (0.39) | MAPTALDH1A1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084593-A | Cyanine, aniline dyes for heat sensitive recording elements | RICOH COMPANY, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4939117-A | Leuco dyes and recording material employing the same | RICOH COMPANY, LTD. (JP) | 1990-07-03 | — | — | US | disclosed |