SCHEMBL9750018

SCHEMBL9750018

Cc1cc(N)c(S(=O)(=O)O)cc1N=Nc1cc(S(=O)(=O)CCOS(=O)(=O)O)ccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.40
TP53 P04637 2/20 0.40
CREBBP Q92793 1/20 0.40
SENP2 Q9HC62 5/20 0.35
SENP1 Q9P0U3 4/20 0.35
SUMO2 P61956 4/20 0.35
SUMO1 P63165 4/20 0.35
SENP7 Q9BQF6 4/20 0.35
SENP3 Q9H4L4 3/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
ENPP2 Q13822 3/20 0.32
THRB P10828 2/20 0.32
ALDH1A1 P00352 4/20 0.32
ATIC P31939 1/20 0.32
KDM4E B2RXH2 1/20 0.32
APP P05067 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7718708 0.86 BRD4 (0.44) BRD4TP53CREBBPSENP2SENP1
SCHEMBL9750126 0.85 BRD4 (0.41) BRD4TP53CREBBPSENP2SENP1
SCHEMBL7717676 0.84 SENP2 (0.43) BRD4TP53CREBBPSENP2SENP1
SCHEMBL9749734 0.82 THRB (0.43) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL7712986 0.81 SENP2 (0.45) BRD4TP53CREBBPSENP2SENP1
SCHEMBL9750184 0.80 SENP2 (0.43) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL2483846 0.78 BRD4 (0.37) BRD4TP53CREBBPSENP2SENP1
SCHEMBL2483843 0.78 BRD4 (0.37) BRD4TP53CREBBPSENP2SENP1
SCHEMBL13793183 0.78 BRD4 (0.47) BRD4TP53CREBBPSENP2SENP1
SCHEMBL13793159 0.76 THRB (0.45) BRD4TP53CREBBPSENP2SENP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5093484-A Water soluble; colorfast shades on cotton BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed