SCHEMBL9750126

SCHEMBL9750126

Cc1cc(N)c(S(=O)(=O)O)cc1N=Nc1cc(Cl)c(S(=O)(=O)CCOS(=O)(=O)O)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.41
TP53 P04637 2/20 0.41
CREBBP Q92793 1/20 0.41
SENP2 Q9HC62 4/20 0.34
SUMO2 P61956 3/20 0.34
SUMO1 P63165 3/20 0.34
SENP7 Q9BQF6 3/20 0.34
SENP1 Q9P0U3 3/20 0.34
SENP3 Q9H4L4 2/20 0.34
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ATIC P31939 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
APP P05067 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750433 0.88 TP53 (0.34) BRD4TP53CREBBPMEN1KMT2A
SCHEMBL9750018 0.85 BRD4 (0.40) BRD4TP53CREBBPSENP2SUMO2
SCHEMBL9750092 0.83 SENP2 (0.40) SENP2SUMO2SUMO1SENP7SENP1
SCHEMBL7712986 0.83 SENP2 (0.45) BRD4TP53CREBBPSENP2SUMO2
SCHEMBL7718708 0.80 BRD4 (0.44) BRD4TP53CREBBPSENP2SUMO2
SCHEMBL9749734 0.77 THRB (0.43) SENP2SUMO2SUMO1SENP7SENP1
SCHEMBL7717676 0.77 SENP2 (0.43) BRD4TP53CREBBPSENP2SUMO2
SCHEMBL9750184 0.75 SENP2 (0.43) SENP2SUMO2SUMO1SENP7SENP1
SCHEMBL9558895 0.75 CA2 (0.46) CA12CA1CA2CA9ALDH1A1
SCHEMBL8951874 0.75 CA2 (0.39) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5093484-A Water soluble; colorfast shades on cotton BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed