Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573445 | 0.87 | CNR2 (0.47) | EGFRERBB2CNR2NR1I2SLC16A3 | |
| SCHEMBL9822870 | 0.87 | EGFR (0.40) | EGFRERBB2NR1I2PKMMAPT | |
| SCHEMBL9749949 | 0.85 | MEN1 (0.50) | HDAC3HDAC1HDAC2EGFRERBB2 | |
| SCHEMBL9502935 | 0.84 | MAPT (0.49) | CNR2NR1I2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10473319 | 0.83 | EGFR (0.47) | HDAC3HDAC1HDAC2EGFRERBB2 | |
| SCHEMBL610171 | 0.83 | MEN1 (0.56) | HDAC1EGFRERBB2CNR2GAA | |
| SCHEMBL9823062 | 0.82 | ALDH1A1 (0.43) | EGFRERBB2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL24359339 | 0.82 | CNR2 (0.52) | EGFRCNR2NR1I2SLC16A3SLC16A1 | |
| SCHEMBL609089 | 0.77 | EGFR (0.50) | EGFRERBB2CNR2MAPTGAA | |
| SCHEMBL9822955 | 0.77 | MEN1 (0.53) | EGFRERBB2CNR2NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084593-A | Cyanine, aniline dyes for heat sensitive recording elements | RICOH COMPANY, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |