Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359339 | 0.94 | CNR2 (0.52) | CNR2CA12CA1CA2CA7 | |
| SCHEMBL22340749 | 0.88 | CNR2 (0.54) | CNR2MAPTUSP2LMNACYP1A2 | |
| SCHEMBL3945201 | 0.88 | CA12 (0.48) | CNR2CA12CA1CA2CA7 | |
| SCHEMBL9750095 | 0.87 | HDAC3 (0.44) | CNR2EGFRSMN1; SMN2PDGFRBKDR | |
| SCHEMBL9915648 | 0.87 | AHR (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9749949 | 0.87 | MEN1 (0.50) | CNR2CA1CA2EGFRSLC16A3 | |
| SCHEMBL7153351 | 0.85 | EGFR (0.50) | CNR2EGFRALDH1A1GAAMAPT | |
| SCHEMBL11808213 | 0.85 | CNR2 (0.49) | CNR2SLC16A3SLC16A1AOC3USP2 | |
| SCHEMBL13568699 | 0.84 | PTGES (0.51) | SMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL22340477 | 0.83 | CNR2 (0.60) | CNR2MAPTUSP2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442800-B2 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-10-28 | — | — | US | claimed |
| CN-101184711-A | Nucleophilic heterocyclic carbene derivatives of pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-05-21 | — | — | CN | claimed |
| EP-1885669-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | Promerus LLC (US) | 2008-02-13 | — | — | EP | claimed |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2006-12-21 | — | — | US | claimed |
| WO-2006128097-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | PROMERUS LLC (US) | 2006-11-30 | — | — | WO | claimed |
| CN-115448909-B | N-carbazolyl-1H-pyrrole-2-carboxamide and application thereof as ligand in copper-catalyzed C-N coupling reaction | 中山大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-115448909-A | N-carbazolyl-1H-pyrrole-2-formamide and application thereof as ligand in copper-catalyzed C-N coupling reaction | 中山大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-109562025-B | Powder-liquid type inner material for denture base | 株式会社德山齿科 | 2022-03-22 | — | — | CN | disclosed |
| US-10973740-B2 | Powder-liquid type denture base lining material | TOKUYAMA DENTAL CORPORATION (JP) | 2021-04-13 | — | — | US | disclosed |
| EP-3488842-B1 | POWDER-LIQUID TYPE DENTAL PLATE LINER | TOKUYAMA DENTAL CORP (JP) | 2021-03-24 | — | — | EP | disclosed |
| CN-107920876-B | Reference denture base, reference denture, denture creation tool, and denture creation method | 株式会社德山齿科 | 2020-10-23 | — | — | CN | disclosed |
| EP-3342370-B1 | REFERENCE DENTAL PLATE, REFERENCE DENTURE, DENTURE FABRICATION KIT AND DENTURE FABRICATION METHOD | TOKUYAMA DENTAL CORP (JP) | 2020-10-14 | — | — | EP | disclosed |
| US-20040245432-A1 | Two-photon absorbing polymerization method, two-photon absorbing optical recording material and two-photon absorbing optical recording method | FUJI PHOTO FILM CO., LTD. | 2004-12-09 | — | — | US | disclosed |
| US-20040048948-A1 | Adhesive composition for denture base relining material and dental curable composition | TOKUYAMA DENTAL CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1348416-A1 | ADHESIVE COMPOSITIONS FOR BACK-COATING DENTAL PLATE AND HARDENING COMPOSITIONS FOR DENTAL USE | TOKUYAMA CORPORATION (JP) | 2003-10-01 | — | — | EP | disclosed |
| EP-1313560-A1 | CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION | YALE UNIVERSITY (US) | 2003-05-28 | — | — | EP | disclosed |
| US-6562989-B2 | Bicyclopentyl iron ligand and transition metal catalyst | YALE UNIVERSITY | 2003-05-13 | — | — | US | disclosed |
| US-20030008768-A1 | Catalyst for aromatic C-O, C-N, and C-C bond formation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |
| WO-2002011883-A1 | CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION | YALE UNIVERSITY (US) | 2002-02-14 | — | — | WO | disclosed |
| US-5158949-A | 1,3-DIOXOLANE DERIVATIVES AS CHOLESTEROL-LOWERING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1992-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10973740-B2 | Powder-liquid type denture base lining material | TAS2R8, TAS2R1, AOC1 | CNR2 4342/4885CA12 4358/4885CA1 2369/4885 |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | NDC1, DDC, PDCD1LG2 | CNR2 1149/4885CA12 426/4885CA1 1818/4885 |
| US-20040048948-A1 | Adhesive composition for denture base relining material and dental curable composition | TAS2R42, TAF1, CAD | CNR2 4486/4885CA12 234/4885CA1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.