Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.46 |
| ▸ | MAOA | P21397 | 7/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750274 | 0.89 | MAOB (0.43) | MAOBMAOAACHE | |
| SCHEMBL9750432 | 0.87 | HRH3 (0.48) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL9750442 | 0.83 | TDP1 (0.37) | MAOBMAOAMEN1KMT2AACHE | |
| SCHEMBL11287132 | 0.81 | MPI (0.38) | MEN1KMT2A | |
| SCHEMBL9750240 | 0.80 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL3809912 | 0.78 | POLB (0.43) | MEN1KMT2A | |
| SCHEMBL9734981 | 0.78 | PDK2 (0.39) | — | |
| SCHEMBL11019035 | 0.77 | HRH3 (0.48) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL9750421 | 0.77 | ACHE (0.42) | MAOBKMT2AACHE | |
| SCHEMBL10881205 | 0.76 | PDK2 (0.39) | MAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |