Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750257 | 0.87 | GRIA2 (0.42) | TDP1MPIKMT2AMEN1ALDH1A1 | |
| SCHEMBL9750440 | 0.87 | GRIA2 (0.42) | TDP1MPIKMT2AMEN1ALDH1A1 | |
| SCHEMBL8942200 | 0.87 | GRIA2 (0.42) | TDP1MPIMAOAMAOBBACE1 | |
| SCHEMBL3809912 | 0.83 | POLB (0.43) | TDP1MPIKMT2AMEN1ALDH1A1 | |
| SCHEMBL9750098 | 0.83 | MAOB (0.46) | KMT2AMEN1MAOAMAOBACHE | |
| SCHEMBL9750113 | 0.81 | GRIA2 (0.45) | TDP1MPIBACE1MAPTPOLB | |
| SCHEMBL3819871 | 0.80 | MAPT (0.43) | TDP1MPIKMT2AMEN1ALDH1A1 | |
| SCHEMBL11287132 | 0.78 | MPI (0.38) | TDP1MPIKMT2AMEN1LMNA | |
| SCHEMBL6474703 | 0.75 | HSPA9 (0.42) | TDP1MPIBACE1 | |
| SCHEMBL9734981 | 0.74 | PDK2 (0.39) | TDP1MPIALDH1A1LMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0087706-B1 | CATIONIC HYDRAZONE DYES, THEIR MANUFACTURE AND THEIR USE | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| US-4513142-A | Preparation of cationic methine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-23 | — | — | US | disclosed |
| US-4496719-A | 3H-Indol-2-yl cationic hydrazone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-29 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| EP-0113920-A2 | Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0087706-A2 | Cationic hydrazone dyes, their manufacture and their use | BAYER AG (DE) | 1983-09-07 | — | — | EP | disclosed |
| EP-0074569-A2 | Cationic methine dyes, process for their preparation and their use, in dyeing textile materials and other substrates | BAYER AG (DE) | 1983-03-23 | — | — | EP | disclosed |