Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | FSHR | P23945 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019035 | 0.90 | HRH3 (0.48) | HRH3ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL9750274 | 0.88 | MAOB (0.43) | HRH3NPC1RAB9AMAOBMAOA | |
| SCHEMBL9750098 | 0.87 | MAOB (0.46) | MEN1KMT2AMAOBMAOA | |
| SCHEMBL9750285 | 0.85 | HRH3 (0.43) | HRH3ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL28250868 | 0.84 | POLB (0.48) | HRH3ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL9750421 | 0.84 | ACHE (0.42) | ALOX5KMT2AMAOBTP53 | |
| SCHEMBL9750240 | 0.82 | MEN1 (0.40) | MEN1KMT2ANPC1PDK2CYP3A4 | |
| SCHEMBL8942200 | 0.81 | GRIA2 (0.42) | NPC1MAOBPDK2MAOA | |
| SCHEMBL11287132 | 0.81 | MPI (0.38) | MEN1KMT2A | |
| SCHEMBL9734981 | 0.80 | PDK2 (0.39) | HRH3PDK2CYP3A4GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0087706-B1 | CATIONIC HYDRAZONE DYES, THEIR MANUFACTURE AND THEIR USE | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0074569-B1 | CATIONIC METHINE DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE, IN DYEING TEXTILE MATERIALS AND OTHER SUBSTRATES | BAYER AG (DE) | 1985-06-19 | — | — | EP | disclosed |
| US-4513142-A | Preparation of cationic methine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-23 | — | — | US | disclosed |
| US-4496719-A | 3H-Indol-2-yl cationic hydrazone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-29 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0087706-A2 | Cationic hydrazone dyes, their manufacture and their use | BAYER AG (DE) | 1983-09-07 | — | — | EP | disclosed |
| EP-0074569-A2 | Cationic methine dyes, process for their preparation and their use, in dyeing textile materials and other substrates | BAYER AG (DE) | 1983-03-23 | — | — | EP | disclosed |
| US-4349670-A | Process for the preparation of cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |
| EP-0058863-A1 | Process for the preparation of trimethine dyestuffs | BAYER AG (DE) | 1982-09-01 | — | — | EP | disclosed |
| EP-0023652-A1 | Process for the preparation of cationic dyestuffs | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |