Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892341 | 0.85 | ALDH1A1 (0.48) | TSHRNPC1RAB9AMAPTHPGD | |
| SCHEMBL17946006 | 0.82 | TSHR (0.51) | TSHRKCNJ1NPC1RAB9ACYP3A4 | |
| SCHEMBL12892332 | 0.80 | MAPT (0.46) | TSHRCYP3A4MAPTHPGDKMT2A | |
| SCHEMBL6570236 | 0.78 | MAPT (0.36) | MAPTHPGDKMT2AALDH1A1 | |
| SCHEMBL8049848 | 0.73 | ALDH1A1 (0.44) | TSHRNPC1MAPTHPGDKMT2A | |
| SCHEMBL1247788 | 0.73 | HPGD (0.47) | TSHRCYP3A4MAPTHPGDKMT2A | |
| SCHEMBL367379 | 0.73 | ALDH1A1 (0.39) | TSHRRAB9AMAPTHPGDKMT2A | |
| SCHEMBL12436082 | 0.67 | LMNA (0.60) | TSHRKCNJ1CYP3A4BAZ2BMAPT | |
| SCHEMBL6396275 | 0.66 | ALDH1A1 (0.41) | TSHRHPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL3294203 | 0.66 | TSHR (0.51) | TSHRKCNJ1CYP3A4BAZ2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141846-A | Method for preparing photographic emulsion | POLAROID CORPORATION (US) | 1992-08-25 | — | — | US | disclosed |