Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4B | O94953 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749243 | 0.82 | CPA1 (0.36) | KDM4E | |
| SCHEMBL9565308 | 0.68 | KDM4E (0.44) | KDM4ESLC6A3KDM4C | |
| Potassium Ion SCHEMBL11840378 | 0.64 | KDM4E (0.39) | KDM4EKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL13134298 | 0.64 | THRB (0.40) | KDM4EALDH1A1 | |
| SCHEMBL11879750 | 0.63 | KMT2A (0.39) | KDM4EALDH1A1 | |
| SCHEMBL7289766 | 0.62 | CPA1 (0.46) | KDM4ESLC6A3KDM4C | |
| SCHEMBL7289773 | 0.62 | CPA1 (0.46) | KDM4ESLC6A3KDM4C | |
| SCHEMBL9672400 | 0.62 | KDM4E (0.45) | KDM4EKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL16682792 | 0.61 | MAPK1 (0.40) | KDM4ESLC6A3ALDH1A1KDM4C | |
| SCHEMBL990477 | 0.61 | DPP4 (0.49) | KDM4ESLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |