Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749094 | 0.85 | FOLH1 (0.41) | CPA3FOLH1 | |
| SCHEMBL9750233 | 0.82 | KDM4E (0.40) | KDM4E | |
| SCHEMBL7289773 | 0.73 | CPA1 (0.46) | CPA1CPB1CPA3CPB2KDM4E | |
| SCHEMBL7289766 | 0.73 | CPA1 (0.46) | CPA1CPB1CPA3CPB2KDM4E | |
| SCHEMBL9749382 | 0.72 | KDM4E (0.40) | CPA1CPB1CPA3CPB2KDM4E | |
| SCHEMBL10890577 | 0.64 | ALDH1A1 (0.60) | KDM4E | |
| SCHEMBL10890573 | 0.64 | ALDH1A1 (0.60) | KDM4E | |
| SCHEMBL759475 | 0.62 | CPA1 (0.49) | CPA1CPB1CPA3CPB2KDM4E | |
| SCHEMBL6218758 | 0.62 | KDM4E (0.40) | KDM4E | |
| SCHEMBL7283545 | 0.62 | ALDH1A1 (0.54) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |