Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.37 |
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265347 | 0.80 | MAOB (0.31) | MAOAMAOB | |
| SCHEMBL27501736 | 0.80 | TSHR (0.35) | MAOAMAOBOPRL1OPRM1OPRK1 | |
| SCHEMBL28798142 | 0.80 | MAOB (0.42) | MAOAMAOB | |
| SCHEMBL27889476 | 0.80 | MAOB (0.42) | MAOAMAOB | |
| SCHEMBL7453568 | 0.80 | GAA (0.34) | MAOAMAOBOPRL1OPRM1KDM1A | |
| SCHEMBL42288 | 0.80 | MAOB (0.42) | MAOAMAOB | |
| SCHEMBL11780784 | 0.80 | MAOA (0.31) | MAOAMAOB | |
| Ethane SCHEMBL27995166 | 0.79 | MEN1 (0.34) | OPRL1OPRM1OPRK1 | |
| Methylamine SCHEMBL42507 | 0.77 | MAOB (0.40) | MAOAMAOB | |
| SCHEMBL3953873 | 0.77 | TSHR (0.33) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503532-A | A kind of 3- phenyl -3- Benzylbenzofuran ketone compounds and its high-efficiency synthesis method | 湖南大学 | 2019-03-22 | — | — | CN | disclosed |
| US-5116804-A | Leuco dye, dibenzyl oxalate derivative as sensitizer | RICOH COMPANY, LTD. (JP) | 1992-05-26 | — | — | US | disclosed |