Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.31 |
| ▸ | MAOA | P21397 | 4/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27999891 | 0.86 | HDAC4 (0.32) | HDAC4 | |
| SCHEMBL31173770 | 0.82 | TRPA1 (0.30) | — | |
| SCHEMBL27501736 | 0.81 | TSHR (0.35) | MAOBMAOATAAR1HDAC4 | |
| SCHEMBL11780784 | 0.81 | MAOA (0.31) | MAOBMAOATAAR1HDAC4 | |
| SCHEMBL28798142 | 0.81 | MAOB (0.42) | MAOBMAOATAAR1 | |
| SCHEMBL7453568 | 0.81 | GAA (0.34) | MAOBMAOATAAR1HDAC4 | |
| SCHEMBL42288 | 0.81 | MAOB (0.42) | MAOBMAOATAAR1 | |
| SCHEMBL27889476 | 0.81 | MAOB (0.42) | MAOBMAOATAAR1 | |
| SCHEMBL9750269 | 0.80 | MAOA (0.37) | MAOBMAOA | |
| Ethane SCHEMBL27995166 | 0.80 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101597243-B | Synthesis method of 4'-Bromomethyl-2-cyanobiphenyl | ASYMCHEM LIFE SCIENCE TIANJIN CO LTD | 2012-11-21 | — | — | CN | claimed |
| CN-101597243-A | The synthetic method of a kind of 2-cyano group-4 '-bromomethylbiphenyl | ASYMCHEM LIFE SCIENCE TIANJIN (CN) | 2009-12-09 | — | — | CN | claimed |
| WO-2024234082-A1 | GUANIDINYLATED AMPHIPHILIC TOBRAMYCIN DERIVATIVES AND B-LACTAM/B-LACTAMASE INHIBITOR COMBINATIONS FOR TREATMENT OF PSEUDOMONAS AERUGINOSA INFECTIONS | UNIVERSITY OF MANITOBA (CA) | 2024-11-21 | — | — | WO | disclosed |
| CN-1033584-C | Benzo-fused lactams that promote release of growth hormone | MERCK & CO INC (US) | 1996-12-18 | — | — | CN | disclosed |
| US-4342756-A | AS ANTITHROMBOTIC AGENTS AND ANTIASTHMATIC AGENTS | GLAXO GROUP LIMITED (GB) | 1982-08-03 | — | — | US | disclosed |