Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750336 | 0.88 | KDM4E (0.45) | ESR1ESR2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL7798232 | 0.78 | TDP1 (0.42) | ESR1ESR2DPP4GAAKDM4E | |
| SCHEMBL1390701 | 0.74 | RORC (0.38) | ESR1ESR2DPP4MEN1KMT2A | |
| SCHEMBL5536594 | 0.74 | MEN1 (0.50) | ESR1ESR2DPP4MEN1GLA | |
| SCHEMBL5542006 | 0.72 | SHBG (0.48) | ESR1ESR2DPP4MEN1GLA | |
| SCHEMBL5541364 | 0.72 | TDP1 (0.60) | ESR1ESR2DPP4GAANPC1 | |
| SCHEMBL5548100 | 0.70 | SHBG (0.43) | ESR1ESR2DPP4MEN1GLA | |
| SCHEMBL15897955 | 0.70 | POLB (0.43) | ESR1ESR2DPP4MEN1KMT2A | |
| SCHEMBL11857232 | 0.70 | ESR2 (0.49) | ESR1ESR2DPP4KDM4EALDH1A1 | |
| SCHEMBL10460571 | 0.69 | DPP4 (0.42) | ESR1ESR2DPP4MEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230475-B1 | NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |