Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750293 | 0.88 | ESR1 (0.40) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL1390878 | 0.74 | MAPT (0.41) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL1390693 | 0.74 | MAPT (0.41) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL5548009 | 0.74 | MEN1 (0.46) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9748059 | 0.72 | ESR1 (0.56) | ESR1ESR2CHRNA7 | |
| SCHEMBL5543458 | 0.72 | SHBG (0.44) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL5547664 | 0.72 | BRD4 (0.55) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL5546425 | 0.70 | DRD2 (0.48) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL15447322 | 0.69 | KDM4E (0.47) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9749565 | 0.69 | KDM4E (0.47) | KDM4EALDH1A1CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230475-B1 | NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4838924-A | NONPHYTOTOXIC | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |