Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750327 | 1.00 | CTBP2 (0.33) | CTBP2GAAL3MBTL1KDM4ETDP1 | |
| SCHEMBL9748936 | 0.72 | APEX1 (0.51) | GAAKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL10689776 | 0.70 | GAA (0.37) | CTBP2GAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL10689769 | 0.70 | GAA (0.37) | CTBP2GAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL9748851 | 0.66 | HPGD (0.55) | KDM4EALDH1A1HPGD | |
| SCHEMBL4673987 | 0.64 | CTBP2 (0.57) | CTBP2L3MBTL1TDP1HPGD | |
| SCHEMBL9749218 | 0.60 | SLC22A12 (0.38) | — | |
| SCHEMBL3161605 | 0.54 | — | — | |
| SCHEMBL11111573 | 0.54 | — | — | |
| SCHEMBL10445731 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |