Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673984 | 1.00 | CTBP2 (0.57) | CTBP2KMT2AMEN1USP2HPGD | |
| SCHEMBL4677259 | 0.82 | NPC1 (0.49) | KMT2AMEN1USP2HPGDL3MBTL1 | |
| SCHEMBL4677261 | 0.82 | NPC1 (0.49) | KMT2AMEN1USP2HPGDL3MBTL1 | |
| SCHEMBL4677112 | 0.81 | SMN1; SMN2 (0.44) | CTBP2KMT2AMEN1USP2HPGD | |
| SCHEMBL4677116 | 0.81 | SMN1; SMN2 (0.44) | CTBP2KMT2AMEN1USP2HPGD | |
| SCHEMBL4677954 | 0.79 | RAB9A (0.53) | KMT2AMEN1USP2HPGDL3MBTL1 | |
| SCHEMBL4677949 | 0.79 | RAB9A (0.53) | KMT2AMEN1USP2HPGDL3MBTL1 | |
| SCHEMBL1660160 | 0.77 | FFAR1 (0.65) | KMT2AMEN1USP2HPGDL3MBTL1 | |
| SCHEMBL4674189 | 0.76 | ALDH1A1 (0.53) | KMT2AMEN1HPGDHTTRAB9A | |
| SCHEMBL4674194 | 0.76 | ALDH1A1 (0.53) | KMT2AMEN1HPGDHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392639-B1 | PYRUVATE DERIVATIVES | GALILEO LAB INC (US) | 2008-09-17 | — | — | EP | claimed |
| EP-1392639-A4 | PYRUVATE DERIVATIVES | GALILEO LAB INC (US) | 2006-01-25 | — | — | EP | claimed |
| EP-1392639-A1 | PYRUVATE DERIVATIVES | Galileo Laboratories, Inc. (US) | 2004-03-03 | — | — | EP | claimed |
| US-20030013656-A1 | Pyruvate derivatives | ALLOY VENTURES, INC. | 2003-01-16 | — | — | US | claimed |
| WO-2002090314-A1 | PYRUVATE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2002-11-14 | — | — | WO | claimed |
| EP-1392639-B1 | PYRUVATE DERIVATIVES | GALILEO LAB INC (US) | 2008-09-17 | — | — | EP | disclosed |
| EP-1392639-A4 | PYRUVATE DERIVATIVES | GALILEO LAB INC (US) | 2006-01-25 | — | — | EP | disclosed |
| US-6916850-B2 | Pyruvate derivatives | GALILEO PHARMACEUTICALS, INC. (US) | 2005-07-12 | — | — | US | disclosed |
| US-6900218-B2 | Pyruvate derivatives | GALILEO PHARMACEUTICALS, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1392639-A1 | PYRUVATE DERIVATIVES | Galileo Laboratories, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| US-6608196-B2 | Structurally diverse; parallel approach | GALILEO PHARMACEUTICALS, INC. | 2003-08-19 | — | — | US | disclosed |
| US-20030100750-A1 | Process for solid supported synthesis of pyruvate-derived compounds | EDISON PHARMACEUTICALS, INC. | 2003-05-29 | — | — | US | disclosed |
| US-20030013656-A1 | Pyruvate derivatives | ALLOY VENTURES, INC. | 2003-01-16 | — | — | US | disclosed |
| US-20030013846-A1 | Pyruvate derivatives | ALLOY VENTURES, INC. | 2003-01-16 | — | — | US | disclosed |
| US-20030013847-A1 | Cytoprotective agents | MONSANTO TECHNOLOGY LLC | 2003-01-16 | — | — | US | disclosed |
| US-20030013657-A1 | Pyruvate derivatives | MONSANTO TECHNOLOGY, LLC. | 2003-01-16 | — | — | US | disclosed |
| WO-2002090314-A1 | PYRUVATE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013847-A1 | Cytoprotective agents | PC, PDK1, PDK2 | CTBP2 4183/4885KMT2A 3599/4885MEN1 4674/4885 |
| US-20030013657-A1 | Pyruvate derivatives | PC, PDK1, PDK4 | CTBP2 4413/4885KMT2A 2023/4885MEN1 4453/4885 |
| US-20030100750-A1 | Process for solid supported synthesis of pyruvate-derived compounds | PC, PDK4, PDK1 | CTBP2 3002/4885KMT2A 1621/4885MEN1 2070/4885 |
| US-20030013846-A1 | Pyruvate derivatives | PC, PDK1, PDK4 | CTBP2 4413/4885KMT2A 2023/4885MEN1 4453/4885 |
| US-20030013656-A1 | Pyruvate derivatives | PC, PDK1, PDK4 | CTBP2 4413/4885KMT2A 2023/4885MEN1 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.