Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.39 |
| ▸ | PRNP | P04156 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749437 | 0.90 | APEX1 (0.41) | APEX1ALDH1A1HSD17B10GAATSHR | |
| SCHEMBL9749643 | 0.89 | APEX1 (0.40) | APEX1ALDH1A1HSD17B10GAATSHR | |
| SCHEMBL9749161 | 0.88 | APEX1 (0.39) | APEX1ALDH1A1HSD17B10GAATSHR | |
| SCHEMBL9750324 | 0.72 | CTBP2 (0.33) | ALDH1A1GAAHPGDKDM4ETDP1 | |
| SCHEMBL9748851 | 0.70 | HPGD (0.55) | ALDH1A1HPGDSMN1; SMN2KDM4EPOLB | |
| SCHEMBL9749305 | 0.69 | ALDH1A1 (0.32) | ALDH1A1HSD17B10GAAHPGDMAPK1 | |
| SCHEMBL9749308 | 0.69 | ALDH1A1 (0.32) | ALDH1A1HSD17B10GAAHPGDMAPK1 | |
| SCHEMBL9749534 | 0.69 | APEX1 (0.54) | APEX1ALDH1A1HSD17B10GAATSHR | |
| SCHEMBL8441393 | 0.69 | APEX1 (1.00) | APEX1ALDH1A1HSD17B10GAATSHR | |
| SCHEMBL10694025 | 0.68 | APEX1 (0.53) | APEX1ALDH1A1HSD17B10GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |