Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575302 | 0.84 | AKR1B10 (0.61) | PLK1AKR1B10AKR1A1AKR1B1ALDH1A1 | |
| SCHEMBL10416214 | 0.84 | AKR1B10 (0.58) | PLK1AKR1B10AKR1A1AKR1B1KDR | |
| SCHEMBL7089895 | 0.83 | AKR1B10 (0.62) | PLK1AKR1B10AKR1A1AKR1B1GAA | |
| SCHEMBL10417713 | 0.82 | AKR1B10 (0.55) | PLK1AKR1B10AKR1A1AKR1B1KDR | |
| SCHEMBL10641624 | 0.81 | AKR1B10 (0.56) | PLK1AKR1B10AKR1A1AKR1B1KDR | |
| SCHEMBL7113675 | 0.81 | AKR1B10 (0.65) | PLK1AKR1B10AKR1A1AKR1B1ALDH1A1 | |
| SCHEMBL18530548 | 0.81 | PLK1 (0.49) | PLK1AKR1B10AKR1A1AKR1B1MTNR1A | |
| SCHEMBL10417230 | 0.81 | AKR1B10 (0.58) | PLK1AKR1B10AKR1A1AKR1B1KDR | |
| SCHEMBL7110674 | 0.81 | AKR1B10 (0.53) | PLK1AKR1B10AKR1A1AKR1B1KDR | |
| SCHEMBL10416215 | 0.81 | AKR1B10 (0.61) | PLK1AKR1B10AKR1A1AKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935514-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | claimed |
| US-4935513-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | claimed |
| EP-0212569-B1 | THIATION PROCESS | ETHYL CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| US-4935514-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4935510-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4663452-A | Thiation process | ETHYL CORPORATION (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0212569-A2 | Thiation process | ETHYL CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |