Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7113523 | 0.99 | AKR1B10 (0.52) | AKR1B10AKR1A1AKR1B1PLK1KLK1 | |
| SCHEMBL10416214 | 0.86 | AKR1B10 (0.58) | AKR1B10AKR1A1AKR1B1PLK1ALDH1A1 | |
| SCHEMBL10415791 | 0.83 | AKR1B10 (0.60) | AKR1B10AKR1A1AKR1B1PLK1MAPT | |
| SCHEMBL10417230 | 0.83 | AKR1B10 (0.58) | AKR1B10AKR1A1AKR1B1PLK1ALDH1A1 | |
| SCHEMBL9575302 | 0.82 | AKR1B10 (0.61) | AKR1B10AKR1A1AKR1B1PLK1ALDH1A1 | |
| SCHEMBL7111907 | 0.81 | PLK1 (0.45) | PLK1KLK1KLK5ALDH1A1MAPT | |
| SCHEMBL7089895 | 0.81 | AKR1B10 (0.62) | AKR1B10AKR1A1AKR1B1PLK1MAPT | |
| Hydrochloric Acid SCHEMBL7109814 | 0.81 | PLK1 (0.44) | PLK1KLK1KLK5ALDH1A1MAPT | |
| SCHEMBL10417713 | 0.81 | AKR1B10 (0.55) | AKR1B10AKR1A1AKR1B1PLK1MEN1 | |
| Acetic Acid Methyl Ester SCHEMBL9750460 | 0.81 | PLK1 (0.57) | AKR1B10AKR1A1AKR1B1PLK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6600072-B2 | Cardiovascular disorders; antiischemic agents; antiarrhythmia agents | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-07-29 | — | — | US | claimed |
| US-20030013760-A1 | Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them | BRENDEL JOACHIM (DE) | 2003-01-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013760-A1 | Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them | TNNI3, TNNT2, SCN1B | AKR1B10 1228/4885AKR1A1 724/4885AKR1B1 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.