SCHEMBL9750532

SCHEMBL9750532

CC(C)(C)Nc1nc(C(F)(F)F)c(C(=O)Cl)o1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750601 0.86 CCNE2 (0.32) TP53
SCHEMBL9750623 0.83 NPC1 (0.35) TP53
SCHEMBL9750615 0.79 KDM4E (0.41)
SCHEMBL9750700 0.77 CNR2 (0.35) TP53
SCHEMBL9750619 0.77 HDAC4 (0.38) TP53
SCHEMBL9750593 0.76 CFTR (0.40)
SCHEMBL9750684 0.76 TP53 (0.36) TP53
SCHEMBL2145183 0.75
SCHEMBL9750636 0.68 KDM4E (0.40)
SCHEMBL9750657 0.63 KDM4E (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5000775-A 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes MONSANTO COMPANY (US) 1991-03-19 US claimed
US-5000775-A 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes MONSANTO COMPANY (US) 1991-03-19 US disclosed