Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750615 | 0.86 | KDM4E (0.41) | NPSR1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9750601 | 0.84 | CCNE2 (0.32) | LMNATP53HTT | |
| SCHEMBL9750532 | 0.83 | TP53 (0.31) | TP53 | |
| SCHEMBL9750619 | 0.76 | HDAC4 (0.38) | TP53CFTR | |
| SCHEMBL9750700 | 0.76 | CNR2 (0.35) | NPC1TP53 | |
| SCHEMBL9750636 | 0.75 | KDM4E (0.40) | NPSR1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9750593 | 0.74 | CFTR (0.40) | NPC1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9750684 | 0.74 | TP53 (0.36) | NPSR1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL9750657 | 0.71 | KDM4E (0.43) | NPSR1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9750665 | 0.70 | KDM4E (0.40) | NPSR1ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | claimed |