Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.31 |
| ▸ | ACR | P10323 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750619 | 0.82 | HDAC4 (0.38) | CFTRHDAC4HDAC6 | |
| SCHEMBL9750684 | 0.80 | TP53 (0.36) | KDM4EALDH1A1HDAC4HDAC6 | |
| SCHEMBL9750700 | 0.77 | CNR2 (0.35) | KMT2AHDAC4NPC1RAB9A | |
| SCHEMBL9750532 | 0.76 | TP53 (0.31) | — | |
| SCHEMBL9750623 | 0.74 | NPC1 (0.35) | CFTRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9750615 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1HPGDHDAC4HDAC6 | |
| SCHEMBL15087834 | 0.61 | MLYCD (0.58) | CFTRHDAC4ACSS2NPC1RAB9A | |
| SCHEMBL9750657 | 0.59 | KDM4E (0.43) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL9750598 | 0.58 | KDM4E (0.42) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL20500074 | 0.57 | ALDH1A1 (0.48) | CFTRMEN1ALDH1A1KMT2AACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |