Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.35 |
| ▸ | CNR1 | P21554 | 10/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.30 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.30 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.30 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750619 | 0.82 | HDAC4 (0.38) | TP53HDAC4 | |
| SCHEMBL9750684 | 0.80 | TP53 (0.36) | TP53HDAC4 | |
| SCHEMBL9750601 | 0.79 | CCNE2 (0.32) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL9750532 | 0.77 | TP53 (0.31) | TP53 | |
| SCHEMBL9750593 | 0.77 | CFTR (0.40) | KMT2ANPC1RAB9AHDAC4 | |
| SCHEMBL9750623 | 0.76 | NPC1 (0.35) | NPC1TP53 | |
| SCHEMBL9750615 | 0.75 | KDM4E (0.41) | HDAC4 | |
| SCHEMBL9750657 | 0.60 | KDM4E (0.43) | KMT2AHDAC4 | |
| SCHEMBL9119278 | 0.60 | CNR1 (0.55) | CNR2CNR1RORCNPC1RAB9A | |
| SCHEMBL9750598 | 0.59 | KDM4E (0.42) | KMT2ANPC1RAB9AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |