Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2145287 | 0.90 | ALDH1A1 (0.44) | SLC26A6ALDH1A1MAPTSMN1; SMN2C1R | |
| SCHEMBL9750654 | 0.87 | KDM4E (0.40) | SLC26A6ALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL9750580 | 0.87 | P2RY12 (0.45) | SLC26A6ALDH1A1MAPTSMN1; SMN2P2RY12 | |
| SCHEMBL9750741 | 0.86 | MAPT (0.49) | ALDH1A1MAPTTP53SMN1; SMN2RAB9A | |
| SCHEMBL10480148 | 0.81 | KDM4E (0.46) | ALDH1A1MAPTTP53SMN1; SMN2RAB9A | |
| SCHEMBL9751045 | 0.80 | MAPT (0.46) | ALDH1A1MAPTSMN1; SMN2P2RY12RAB9A | |
| SCHEMBL2145615 | 0.80 | HTT (0.49) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL12680960 | 0.79 | P2RY1 (0.68) | P2RY1 | |
| SCHEMBL9750657 | 0.79 | KDM4E (0.43) | ALDH1A1MAPTPOLBHPGDHDAC4 | |
| SCHEMBL9750598 | 0.78 | KDM4E (0.42) | ALDH1A1MAPTRAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |