Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750596 | 0.87 | SLC26A6 (0.49) | P2RY12ALDH1A1P2RY1POLBSLC26A6 | |
| SCHEMBL2145287 | 0.86 | ALDH1A1 (0.44) | ALDH1A1P2RY1POLBSLC26A6KDM4E | |
| SCHEMBL9750741 | 0.82 | MAPT (0.49) | ALDH1A1POLBKDM4EMAPTDHODH | |
| SCHEMBL9750654 | 0.79 | KDM4E (0.40) | NLRP3ALDH1A1SLC26A6KDM4EMAPT | |
| SCHEMBL10480148 | 0.78 | KDM4E (0.46) | ALDH1A1P2RY1KDM4EMAPTHDAC4 | |
| SCHEMBL9750617 | 0.77 | KDM4E (0.40) | ALDH1A1KDM4EMAPTHDAC4HDAC6 | |
| SCHEMBL9751045 | 0.76 | MAPT (0.46) | P2RY12ALDH1A1KDM4EMAPTDHODH | |
| SCHEMBL2145615 | 0.76 | HTT (0.49) | ALDH1A1TRPM8KDM4EMAPTDHODH | |
| SCHEMBL12680960 | 0.76 | P2RY1 (0.68) | P2RY1 | |
| SCHEMBL9750657 | 0.76 | KDM4E (0.43) | ALDH1A1POLBKDM4EMAPTHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |