Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750741 | 0.88 | MAPT (0.49) | MAPTKDM4EGAADHODHHTT | |
| SCHEMBL9750654 | 0.81 | KDM4E (0.40) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL9750596 | 0.80 | SLC26A6 (0.49) | MAPTKDM4EGAAHTTP2RY12 | |
| SCHEMBL10480148 | 0.79 | KDM4E (0.46) | MAPTKDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9750657 | 0.79 | KDM4E (0.43) | MAPTKDM4EHIF1AKMT2AALDH1A1 | |
| SCHEMBL2145287 | 0.79 | ALDH1A1 (0.44) | MAPTKDM4EHTTSMN1; SMN2MEN1 | |
| SCHEMBL9750598 | 0.78 | KDM4E (0.42) | MAPTKDM4EHIF1AKMT2AALDH1A1 | |
| SCHEMBL9750615 | 0.77 | KDM4E (0.41) | MAPTKDM4EHIF1AALDH1A1HPGD | |
| SCHEMBL9750580 | 0.76 | P2RY12 (0.45) | MAPTKDM4EGAADHODHP2RY12 | |
| SCHEMBL9750624 | 0.76 | KDM4E (0.45) | MAPTKDM4EGAATARBP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |